Skip to main content

Vaccine Development Solutions

Accelerate your early-stage development with a comprehensive suite of in vivo and in vitro services designed to generate actionable data to set your program up for long-term success.
Request a consultation

Access our comprehensive discovery and development services to accelerate vaccine development

 In today's rapidly changing global health landscape, the need for effective vaccines against new and emerging pathogens has never been more critical. Traditional vaccine development processes can be slow, costly and often struggle to keep pace with evolving infectious diseases. How can researchers and pharmaceutical companies accelerate the discovery and development of novel vaccines to protect global populations more efficiently?

Advance your vaccine candidates with confidence through our integrated suite of discovery-stage testing services, tailored to support the development of both human and veterinary vaccines against a wide range of viral and bacterial pathogens. With over 40 years of experience, we bring deep scientific expertise and proven capabilities across all major vaccine platforms—including live-attenuated, inactivated, subunit, mRNA, viral vector and DNA-based vaccines. Through efficient operations, scientific expertise, effective project management and flexible study design and start times, we provide time and cost savings while delivering on-time execution and delivery.

Why choose Labcorp?

  • Broad end-to-end services from discovery to IND

  • Integrated in vivo and in vitro services reduce study administration cost and tech transfer delays

  • More than 60,000 sq ft of vivarium space and priority access to a variety of host species

ACCESS THE BROCHURE

ACCESS THE BROCHURE

Trust in an experienced partner

Leverage our scientific expertise and decades of experience for your next vaccine development project. Download the brochure to explore our experience data and learn how a partnership leads to cost and time savings.

Vaccine development and solution-based discovery 

We work with all common vaccine types: subunit, live/attenuated, inactivated and toxoid

  • In vitro capabilities
    • Humoral immune response analysis: Analyze various antibody response types in the well-equipped laboratories using ELISA, neutralization assays, HAI and other tests
    • Cell-mediated immune response: Decipher Th1 and Th2 responses by ELISpot in a dedicated tissue culture facility 
  • In vivo capabilities
    • Immunogenicity studies: Select from a variety of host species ranging from rodents to nonhuman primates with rapid study starts and scalability from a few to a large number of animals
    • Efficacy/challenge: Evaluate your vaccine’s efficacy in our vivariums supporting up to BSL2 pathogens in custom-developed or standard research models

       

Immunogenicity Studies

Immunogenicity studies are a combination of in vivo and in vitro services providing you with a complete evaluation of the immunogenicity of your test vaccines. We work with you as part of a comprehensive development plan to identify a suitable host species (based on the nature of the vaccine) and to recommend sample analysis methods. 

Efficacy/Challenge Studies

Following satisfactory immunogenicity results, efficacy or challenge studies can be conducted using a standard or custom animal model. Pathogens up to BSL2 can be tested in our state-of-the-art vivariums in studies ranging in size from small pilot studies to larger, complex designs. Samples originating from these in vivo studies can be transferred to our laboratories for further analysis. 

Learn more about our Rabies Vaccine and Antiviral Testing Services

Veterinary vaccine development 

Veterinary vaccine development is crucial for animal health, public safety and food security, but development faces many challenges. Labcorp helps you streamline vaccine development with operational efficiency and flexible study design. With insights gleaned from more than 40 years' experience and ~150 efficacy, immunogenicity and general safety studies initiated annually, we provide consultation and efficient execution to support your project success within regulatory guidelines. 

Doctor or nurse in a laboratory preparing a vaccine for a patient.

Why Clients Choose Us: Hear Their Stories

“I want to extend my sincere thanks to you for your performance demonstrated during the challenge phase of our preclinical vaccine study. By all accounts the quality and workmanship of the service provided has been exceptional. The efforts of your management team to work expeditiously, intelligently and honestly has been key for successful execution of this challenging experiment. It has truly been a pleasure to work with you and we look forward to continuing this practice in the future.”
 

– Large Pharma Client

Frequently asked questions

We have a wide range of animal models suitable for vaccine studies, including small and large animal models. Our experienced team can help select the most appropriate models for your specific vaccine candidate and target disease.

Yes, we offer expertise in various innovative delivery platforms, including mRNA vaccines, viral vectors and nanoparticle-based systems. Our team can help you explore and implement these cutting-edge technologies for your vaccine candidates.

We provide end-to-end support, including rapid prototype development for proof-of-concept studies, early-stage safety assessments and scalable manufacturing processes. Our integrated approach enables a smooth transition from discovery to early development phases.

We maintain strict quality control processes, adhere to GLP principles where applicable and employ experienced staff. Our advanced data management systems maintain data integrity and facilitate comprehensive analysis for informed decision-making.

From early discovery to regulatory submission and beyond, our nonclinical development solutions help derisk your program, accelerate timelines and optimize decision-making.